NAVIFY® Mutation Caller*

Secondary analysis purpose-built for Roche Sample Prep Reagents


A cloud-based secondary analysis solution with next-generation sequencing variant calling methods to support the Roche KAPA portfolio of Sample Prep Reagents.

NAVIFY® Mutation Caller*

Secondary analysis purpose-built for Roche Sample Prep Reagents


A cloud-based secondary analysis solution with next-generation sequencing variant calling methods to support the Roche KAPA portfolio of Sample Prep Reagents.

Save time in pipeline selection and optimization

The Roche KAPA Library Preparation and Target Enrichment kits have been optimized to enable targeting of difficult-to-capture regions and offer greater capture uniformity within a streamlined workflow. Now with NAVIFY Mutation Caller, performance optimization has been extended further downstream to offer a secondary analysis solution explicitly tuned for the Roche Sample Prep Portfolio human catalog and custom panels for both KAPA HyperCap and KAPA HyperPETE* workflows.

NAVIFY Mutation Caller offers multiple pipelines in support of KAPA HyperPETE and KAPA HyperCap* reagents.

Streamlined secondary analysis

NAVIFY Mutation Caller provides variant calling algorithms that have been selected based on their sensitivity and specificity for Roche Sample Prep Reagents. But for additional optimization to a lab’s specific wet lab workflow and chosen sequencing coverage, users can further tune parameter settings. Genotype concordance to reference samples further empowers the lab to assess performance. And once pipeline parameter settings are fixed and saved, the NAVIFY Mutation Caller user interface positions lab technicians and scientists to process samples and review results with efficiency, keeping turnaround times low.

Pair with NAVIFY Mutation Profiler for somatic oncology

Interpret the results from secondary analysis for KAPA somatic panels by importing results to NAVIFY Mutation Profiler.

More than just secondary analysis

With a user-friendly interface, NAVIFY Mutation Caller enables administrators to easily onboard new KAPA human custom panels, as well as to better manage users. Additional capabilities are built in the software to enhance the user experience:

  • Re-run samples
  • Search samples
  • Filter variants
  • View variant annotations
  • Access audit logs

To compare the performance of your existing secondary pipeline to pipelines offered in NAVIFY Mutation Caller, or to hit the ground running in the analysis of newer Roche KAPA custom or catalog panels you are onboarding, request a demo or software trial version today.

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*In the US, NAVIFY Mutation Profiler and its relates apps are for Research Use Only. Not for use in diagnostic procedures.