Clinical evidence

Clinical decision support enables personalized healthcare


CDS tools have been shown to reduce clinician workloads as well as provide for efficient data review and enhanced clinical documentation. Tumor board teams gain the opportunity to spend more time with patients and personalize healthcare.1

Clinical evidence

Clinical decision support enables personalized healthcare


CDS tools have been shown to reduce clinician workloads as well as provide for efficient data review and enhanced clinical documentation. Tumor board teams gain the opportunity to spend more time with patients and personalize healthcare.1

NAVIFY® portfolio selected publications

NAVIFY Tumor Board

Digital Tumor Board Solutions Have Significant Impact on Case Preparation

Hammer, R. D., et al., 2020. JCO Clinical Cancer Informatics, 4, pp.757-768.

Findings in this publication suggest oncology care teams can benefit from improved workflow and efficiency.

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A digital tumor board solution impacts case discussion time and postponement of cases in tumor boards

Hammer, R. D., et al., 2021. Health and Technology, pp.1-9.

The result of a multi-year research collaboration with the University of Missouri demonstrated how digital tumor board solutions standardized case preparation and reduced case discussion postponement.

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A clinician’s perspective on co-developing and co-implementing a digital tumor board solution

Hammer, R. D. and Prime, M.S., 2020. Health Informatics Journal, 26(3), pp.2213-2221.

The University of Missouri School of Medicine and Roche co-developed a digital solution.

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A New Software Platform to Improve Multidisciplinary Tumor Board Workflows and User Satisfaction: A Pilot Study

Krupinski, E. A., et al., 2018. Journal of pathology informatics, 9.

A pilot of NAVIFY Tumor Board showed reduced meeting preparation time and improved user satisfaction.

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NAVIFY Mutation Profiler

Assessment of a highly curated somatic oncology database

Stephanie J. Yaung, Ph.D. 2020. JMD Journal, Vol. 22, No. 11

The accuracy level of a cloud-based CE-IVD software that aids in interpreting clinically relevant variants detected in somatic oncology next-generation sequencing tests.

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Digital health perspectives

Challenges for the evaluation of digital health solutions—A call for innovative evidence generation approaches

Guo, C., et al., 2020. npj Digital Medicine, 3(1), pp.1-14.

This study shares innovative and pragmatic approaches to evolve traditional evidence generation.

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Abstracts and posters from scientific meetings

NAVIFY Tumor Board

A Mixed Methods Study for the Evaluation of a Digital Health Solution for Cancer Multidisciplinary Team Meetings Using Simulation-based Research Methods

Gardner C., et al. Presented at ASCO 2020.

Simulated lung cancer multidisciplinary team meetings tested NAVIFY Tumor Board.

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Clinical decision support applications

A Digital Solution to Enable Improved Implementation and Usability of NCCN Guidelines®

Guo, C., et al. JNCCN 18(3.5), pp.BIO20-026. Presented at NCCN2020.

Preliminary evaluation of NAVIFY Guidelines app showed a decrease in steps to access clinical practice guidelines.

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Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer

Perakis SO, Weber S, Zhou Q, et al. Presented at ESMO2020.

An in-depth evaluation of a cell-free DNA from patients with metastatic breast, colorectal or non-small cell lung cancer.

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Real-world evidence

Clinical impact of adherence to NCCN biomarker testing guidelines on survival for patients with advanced non-squamous non-small-cell lung cancer

John A., et al. DOI: https://doi.org/10.6004/jnccn.2019.7441. Presented at 2020 NCCN Annual Meeting.

Adherence to biomarker testing guidelines may be associated with longer survival in patients with lung cancer.

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  1. Hammer, R. D. and Prime, M. S. (2020) ‘A clinician’s perspective on co-developing and co-implementing a digital tumor board solution’, Health Informatics Journal, 26(3), p2213-2221.